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Blood Glucose

What is Blood Glucose?

Plasma glucose, commonly known as blood sugar, is a primary energy source for the body's cells and is critical for normal bodily function. It is particularly important for brain function, as the brain primarily uses glucose for energy. Maintaining stable blood glucose levels is vital for overall health, as it ensures a continuous energy supply to the body's tissues and organs. The body tightly regulates these levels through hormones like insulin and glucagon.

Hypoglycemia, or low blood glucose, can occur due to various factors such as excessive insulin production, insufficient dietary intake, or certain medical conditions. Hypoglycemia can lead to symptoms like dizziness, sweating, confusion, shaking, and in severe cases, loss of consciousness or seizures. Chronic low blood glucose can be particularly harmful to the brain and can impair cognitive function and nervous system health.

Hyperglycemia, or high blood glucose, is commonly associated with diabetes when the body either doesn’t produce enough insulin (Type 1 Diabetes) or cannot effectively use the insulin it produces (Type 2 Diabetes). Persistent hyperglycemia can lead to serious complications, including kidney damage, nerve damage, heart disease, and vision problems. It can cause symptoms like frequent urination, increased thirst, fatigue, and blurred vision. The diuretic effect can potentially lead to the loss of electrolytes like sodium and potassium, affecting their balance in the body.

To maintain healthy blood glucose levels:

  • Adopt a balanced diet that includes complex carbohydrates, fiber, lean proteins, and healthy fats while limiting refined sugars and processed foods.

  • Engage in regular physical activity, as exercise helps improve insulin sensitivity and glucose uptake by the body's cells.

  • If you have diabetes, work closely with your healthcare provider to monitor your blood glucose levels and manage your condition through medication, diet, and lifestyle changes.

  • Be aware of the symptoms of both hypoglycemia and hyperglycemia, and take appropriate action if you experience them, such as adjusting your food intake or seeking medical attention when necessary.

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Measurement Units

Blood Glucose can be measured in: mg/100mL, mg/dL, mg/L, mg%, mmol/L, µg/mL, µmol/L

Reference Ranges by Age and Gender

Reference ranges represent typical values for healthy individuals. Your healthcare provider must interpret your specific results.

Age Range Gender Unit Optimal Normal Source
All ages All genders mmol/L - 3.5 - 5.6 Güemes, 2016

Health Impact

Blood Sugar Regulation​

The most basic and commonly measured indicator of blood sugar regulation. It measures the level of glucose in blood after an overnight fast. Persistent high fasting glucose levels are indicative of diabetes or prediabetes.[Mouri, 2023]

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Academic References

  1. Borg R., Heine R.J., Kuenen J., Nathan D. M., Schoenfeld D., and Zheng H.. Translating the A1C assay into estimated average glucose values (2007). Diabetes Care. DOI: 10.2337/dc08-0545
  2. Fumeron F. Ferritin and transferrin are both predictive of the onset of hyperglycemia in men and women over 3 years (2006). Diabetes Care. View Source
  3. Deary IJ, Frier BM, and Sommerfield AJ. Acute hyperglycemia alters mood state and impairs cognitive performance in people with type 2 diabetes (2004). Diabetes Care. DOI: 10.2337/diacare.27.10.2335
  4. Güemes M, Hussain K, and Rahman SA. What is a normal blood glucose? (2016). Arch Dis Child. DOI: 10.1136/archdischild-2015-308336
  5. Badireddy M. and Mouri MI. Hyperglycemia (2023). View Source
  6. Luong KV and Nguyen LT. The impact of thiamine treatment in the diabetes mellitus (2012). J Clin Med Res. DOI: 10.4021/jocmr890w
  7. Chen TC, Kuo T, McQueen A, and Wang JC. Regulation of Glucose Homeostasis by Glucocorticoids (2015). Adv Exp Med Biol. DOI: 10.1007/978-1-4939-2895-8_5
  8. Sonksen P. H.. Insulin: understanding its action in health and disease (2000). British Journal of Anaesthesia. DOI: 10.1093/bja/85.1.69
  9. Messier C. Glucose improvement of memory: a review (2004). Eur J Pharmacol. DOI: 10.1016/j.ejphar.2004.02.043
  10. Kahn CR and Saltiel AR. Insulin signalling and the regulation of glucose and lipid metabolism (2001). Nature. DOI: 10.1038/414799a
  11. Alaei Shahmiri F, Sherriff J, Soares MJ, and Zhao Y. High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized double-blind cross-over trial (2013). Eur J Nutr. DOI: 10.1007/s00394-013-0534-6
  12. Ekhzaimy A., Khan HA, Masood A, Sakharkar MK, and Sherwani SI. Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients (2016). Biomark Insights. DOI: 10.4137/BMI.S38440
  13. Gandhi J, Sharma S, and Thau L. Physiology, Cortisol (2023). StatPearls. View Source
  14. Dye L, Lamport DJ, Lawton CL, and Mansfield MW. Impairments in glucose tolerance can have a negative impact on cognitive function: a systematic research review (2009). Neurosci Biobehav Rev. DOI: 10.1016/j.neubiorev.2008.10.008
  15. Meamar R., Rad M.G., and Sharifi M.. The role of pancreas to improve hyperglycemia in STZ-induced diabetic rats by thiamine disulfide (2022). NutrDiabetes. DOI: 10.1038/s41387-022-00211-5

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