Vitamin B6, also known as pyridoxine, is a crucial nutrient that plays a significant role in a wide range of bodily functions. It is essential for protein metabolism, red blood cell production, and the creation of neurotransmitters like serotonin and dopamine. Vitamin B6 is also involved in immune function, brain development, and maintaining normal levels of homocysteine, an amino acid in the blood. Adequate levels of vitamin B6 are necessary for optimal health, including proper nerve function and cognitive health. As a water-soluble vitamin, B6 needs to be regularly consumed in the diet, as the body does not store it in large amounts.
Deficiency in vitamin B6, though relatively rare, can lead to a range of health issues. Symptoms include anemia, skin rashes, cracked and sore lips, a swollen tongue, mood changes, weakened immune function, and in severe cases, confusion and seizures. Vitamin B6 deficiency is often associated with low levels of other B vitamins, such as B12 and folic acid, and can be caused by malabsorption syndromes, certain medications, alcoholism, or an inadequate diet. Vitamin B6's absorption and utilization are influenced by dietary protein, magnesium, and other B vitamins.
Toxicity from vitamin B6 is typically related to excessive supplementation and is rare from food sources. High doses of vitamin B6 over a prolonged period can lead to nerve damage, causing numbness and pain in the hands and feet, and in severe cases, could potentially cause neurological problems. The upper intake level for adults is set to avoid the risk of such nerve damage. To maintain adequate levels of vitamin B6, a diet including poultry, fish, potatoes, chickpeas, bananas, and fortified cereals is recommended. Regular monitoring of vitamin B6 levels is generally not necessary, except for individuals with specific medical conditions or dietary restrictions.
To maintain healthy Vitamin B6 levels:
Consume a varied diet rich in vitamin B6 sources, including poultry, fish, potatoes, non-citrus fruits, chickpeas, and fortified cereals.
Ensure adequate protein intake, as it aids in vitamin B6 absorption and utilization.[Miller, 1985]
Be aware of factors that can deplete vitamin B6, such as excessive alcohol consumption and certain medications.
Consider other nutrients that influence B6 metabolism, like magnesium and other B vitamins. A balanced diet or a B-complex supplement may be beneficial.
Vitamin B6 (Pyridoxine) can be measured in: ng/mL, nmol/L, µg/100mL, µg/dL, µg/L, µg%
Reference ranges represent typical values for healthy individuals. Your healthcare provider must interpret your specific results.
| Age Range | Gender | Unit | Optimal | Normal | Source |
|---|---|---|---|---|---|
| All ages | All genders | ng/mL | - | 9.5 - 24 | Rifai, 2023 |
Important for immune function, as it's involved in the production of antibodies and cytokines. It also aids in the growth and function of immune cells like lymphocytes. B6 deficiency impairs the immune response. [Qian, 2017][Meydani, 1991]
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Vitamin B6 is involved in the conversion of homocysteine to cysteine. Adequate levels of vitamin B6 are necessary to maintain normal homocysteine levels. A deficiency in vitamin B6 can result in elevated homocysteine, which is a risk factor for cardiovascular disease.[Selhub, 1999]
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